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Robert C Cooksey Selected Research

Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)

3/2011Increased hexosamine pathway flux and high fat feeding are not additive in inducing insulin resistance: evidence for a shared pathway.
5/2004Activation of the hexosamine signaling pathway in adipose tissue results in decreased serum adiponectin and skeletal muscle insulin resistance.
6/2002Transgenic mice overexpressing the rate-limiting enzyme for hexosamine synthesis in skeletal muscle or adipose tissue exhibit total body insulin resistance.

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Robert C Cooksey Research Topics

Disease

12Insulin Resistance
10/2012 - 06/2002
6Iron Overload
03/2013 - 12/2007
5Hemochromatosis (Bronze Diabetes)
10/2012 - 11/2004
5Type 2 Diabetes Mellitus (MODY)
03/2011 - 06/2002
4Hyperinsulinism (Hyperinsulinemia)
03/2011 - 05/2004
3Glucose Intolerance
10/2012 - 08/2008
3Obesity
06/2012 - 05/2009
2Hypoxia (Hypoxemia)
01/2016 - 06/2012
2Hypoglycemia (Reactive Hypoglycemia)
01/2016 - 05/2009
1Iron Deficiencies
01/2016
1Metabolic Syndrome (Dysmetabolic Syndrome X)
10/2012
1Inflammation (Inflammations)
10/2012
1Hypertension (High Blood Pressure)
05/2009
1Cross Infection (Nosocomial Infection)
04/2009
1Hepatocellular Carcinoma (Hepatoma)
11/2008
1Bacteremia
04/2008
1Sepsis (Septicemia)
04/2008
1Mitochondrial Diseases (Mitochondrial Disease)
03/2008
1Fibrosis (Cirrhosis)
12/2007
1Hypertrophy
11/2007
1Metabolic Diseases (Metabolic Disease)
09/2007
1Hyperglycemia
12/2005
1Neutropenia
12/2004

Drug/Important Bio-Agent (IBA)

16Glucose (Dextrose)FDA LinkGeneric
01/2016 - 06/2002
8IronIBA
01/2016 - 11/2004
8Insulin (Novolin)FDA Link
06/2012 - 05/2004
6Fatty Acids (Saturated Fatty Acids)IBA
06/2012 - 09/2004
6HexosaminesIBA
03/2011 - 06/2002
4EnzymesIBA
03/2011 - 06/2002
3AdiponectinIBA
10/2012 - 05/2004
3Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)IBA
03/2011 - 06/2002
2ManganeseIBA
03/2013 - 03/2008
2LipidsIBA
03/2011 - 05/2005
2Nonesterified Fatty Acids (NEFA)IBA
05/2009 - 11/2008
2Protein Isoforms (Isoforms)IBA
11/2007 - 08/2002
2LeptinIBA
05/2005 - 08/2002
1Pyruvic Acid (Pyruvate)IBA
01/2016
1Lactic Acid (Lactate)FDA LinkGeneric
01/2016
1Transcription Factors (Transcription Factor)IBA
01/2016
1Pyruvate CarboxylaseIBA
01/2016
1Ferritins (Ferritin)IBA
10/2012
1metal transporting protein 1 (ferroportin)IBA
10/2012
1AntioxidantsIBA
06/2012
1Oxygen (Dioxygen)IBA
06/2012
1CarbohydratesIBA
03/2011
1Proteins (Proteins, Gene)FDA Link
03/2011
1Dietary IronIBA
06/2010
1Chelating AgentsIBA
06/2010
1Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
05/2009
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
05/2009
1GlucocorticoidsIBA
05/2009
1CorticosteroneIBA
05/2009
1Adrenocorticotropic Hormone (ACTH)FDA Link
05/2009
1Drinking WaterIBA
04/2009
1Palmitic Acid (Hexadecanoic Acid)IBA
11/2008
1PalmitatesIBA
11/2008
1Insulin ReceptorIBA
11/2008
1Acyl Coenzyme A (Acyl CoA)IBA
11/2008
1Captopril (Capoten)FDA LinkGeneric
08/2008
1Mycolic Acids (Mycolic Acid)IBA
04/2008
1Adenosine Monophosphate (AMP)IBA
12/2007
1Phosphotransferases (Kinase)IBA
12/2007
1PAS domain kinasesIBA
09/2007
1SteroidsIBA
12/2004
1UDP-N-acetylglucosamine-peptide beta-N-acetylglucosaminyltransferaseIBA
08/2002
1O-GlcNAc transferaseIBA
08/2002
1Polysaccharides (Glycans)IBA
08/2002

Therapy/Procedure

1Fat-Restricted Diet (Diet, Fat Restricted)
03/2011
1Catheters
04/2008